Lymphedema is a chronic swelling of the lower extremity, also called “Elephantiasis”. The disease is caused by a dysfunction of the lymph nodes in the leg. The lymph nodes are a part of a much wider lymphatic circulation. The lymphatic channels collect all remaining fluids in the legs and take them back to the blood circulation. Lymph nodes are important relays for this lymphatic network. When they are impaired, the lymphatic circulation is blocked in the legs and a chronic swelling appears. It is a cause of functional discomfort and alters the quality of life. It is sometimes complicated with episodes of skin infection. A correct diagnosis is essential. Therapy is aimed at reducing the swelling through numerous procedures including manual drainage, machine pressotherapy, multi-layer banding and high-grade compression stockings.